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Hydrolyzed proteins from many by-products of fish, mainly skins and bones, have shown metal chelating capacities, with gelatin and collagen proteins being the frequent sources of derived chelating peptides. There are many interactions of xenobiotic metals and their complexes with proteins of iron metabolism in relation to their use in medical diagnosis, therapeutic application and metal detoxification. Chelators, or chelating agents, are found in biological substances and are utilized for the removal of heavy metal impurities, which can be often toxic, and restore cellular metabolism.
Metal-binding proteins are proteins or protein domains that chelate a metal ion. [1] binding of metal ions via chelation is usually achieved via histidines or cysteines. In some cases this is a necessary part of รขโฌยฆ