This article highlights recent milestones in clinical pgx and challenges that adult and pediatric pgx programs are facing and describes important laboratory aspects such as: Available methodologies, … Overcoming these challenges holds the promise of improving new drug development and ultimately individualizing the selection of appropriate drugs and dosages for individual patients.

However, challenges remain to build further clinical evidence for ad-ditional drugs and diverse populations, to develop feasible clinical decision support systems, and to build economic incentives …

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