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Nayzilam ® (midazolam) nasal spray, civ is a prescription medicine used for the short-term treatment of seizure clusters (also known as acute repetitive seizures) in patients 12 years of age and older. How to give nayzilam nayzilam is a ready-to-use nasal spray that can be given by anyone, whenever seizure clusters occur. After peeling open the blister pack, follow these steps.