In this review, we discuss the current understanding of the pathophysiology of progressive ms and highlight promising treatment approaches as well as auspicious preclinical and clinical Multiple sclerosis is an inflammatory and degenerative disease of the central nervous system which includes the brain, spinal cord and also the optic nerves. clinical characteristicsthe most common … Pathophysiology of multiple sclerosis myelin sheath of a healthy neuron in the central nervous system multiple sclerosis is an inflammatory demyelinating disease of the cns in which activated immune …