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Valacyclovir can help clear both the hsv-1 (cold sores) and hsv-2 (genital herpes) types of infections, but the dosing is different depending on what you are treating. Although valtrex is generally safe and effective at treating cold sores, it shouldnâ€™t be taken by just anyone. If you notice cold sores or any other symptoms of an hsv-1 outbreak, talk to your doctor â€¦

The dose for cold sores is 2000 mg (2 grams) every 12 hours for 1 day. Which drugs or supplements interact with â€¦ Valacyclovir will start working within 2 to 3 days of taking it. But for a cold sore to completely heal, it can take around 2 weeks. To get the fastest results, itâ€™s best to start taking valacyclovir as soon as you â€¦