Maliabeth Johnson Nude - Brightlocal News
Herein, we hypothesized that rpc would mitigate hippocampal synaptic dysfunction and pathological cofilin hyperactivation in an ex vivo model of ischemia. Neuroprotective agents administered post cerebral ischemia have failed so far in the clinic to promote significant recovery. Thus, numerous efforts were redirected towards prophylactic approaches such …
In the present study, we aimed to investigate the effects of rpc on early ischemia-induced excitotoxic processes and synaptic dysfunction in the mouse hippocampus. Various electrophysiological parameters and synaptic-related protein expression changes were measured under normal and ischemic conditions utilizing acute hippocampal slices derived from …
