We conducted a randomized clinical trial to compare the effectiveness of initial attempts at intraosseous or intravenous vascular access in adults who had nontrau-matic out-of-hospital cardiac arrest. Treatment with intravenous or intraosseous calcium compared with saline did not significantly improve sustained return of spontaneous circulation and these results do not support the administration of รขโ‚ฌยฆ Conclusions and relevance among adults with out-of-hospital cardiac arrest, treatment with intravenous or intraosseous calcium compared with saline did not significantly improve sustained รขโ‚ฌยฆ

Among adults with out-of-hospital cardiac arrest, treatment with intravenous or intraosseous calcium compared with saline did not significantly improve sustained รขโ‚ฌยฆ This placebo-controlled randomized clinical trial compares administration of calcium vs saline during out-of-hospital cardiac arrest for sustained return of spontaneous circulation in adults.