After the boys (tm) leave konoha, sakura is left all alone. Luckily, kakashi doesn't abandon his teammates and takes it upon himself to make sakura his apprentice, much to lady tsunade's … Sakura would have had just as much exposure to him as naruto.

Sakura's role in boruto or lack thereof is my personal reason why the boruto series does not fit into the naruto narrative. Sakura is a person that would directly involve herself in the current situation.